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博士&硕士生导师

谭海宁

日期:2021-07-28点击:

谭海宁 博士,教授,博士生导师

国家糖工程技术研究中心副主任

济南市文化西路44号药学院科研楼302

青岛市即墨滨海路72K6-208

E-mail: hainingtan@sdu.edu.cn


学习和工作经历

2009/07至今,山东大学,国家糖工程技术研究中心,任教

2004/092009/07,山东大学,药学院,博士研究生/博士

2000/092004/07,山东大学,药学院,本科/学士


研究方向

1. 蛋白质、多肽药物的化学修饰。

2. 抗肿瘤药物及递送系统研究。

3. 糖类药物研究。

4. 医养健康产品研发。


承担项目

先后主持国家级和省部级课题十余项,横向课题数项,作为课题副组长完成民口和军口国家重大新药创制计划各1项;在Journal of Controlled ReleaseCarbohydrate Polymers等学术期刊发表论文30余篇;获得发明专利4项;参编著作4部;Acs NanoCarbohydrate Polymers等学术期刊审稿人;Current Phamaceutical Biotechnology等杂志客座编辑;中国生物化学与分子生物学会工业生物化学与分子生物学会分会理事,中国药理学会海洋药物药理专业位会员委员。

部分代表论文

1. Huiwen Hou, Juan Wang, Jie Wang, Wen Tang, Abdul Sami Shaikh, Yan Li, Jiaai Fu, Lu Lu, Fengshan Wang, Feng Sun*, and Haining Tan*. A Review of Bioactive Peptides: Chemical Modification, Structural Characterization and Therapeutic Applications. Journal of Biomedical Nanotechnology, 16, 1687–1718, 2020.

2. Yan Li, Yumei Fan, Abdul Sami Shaikh, Zhendong Wang, Dongliang Wang and Haining Tan*. Dezhou donkey (Equus asinus) milk a potential treatment strategy for type 2 diabetes. Journal of Ethnopharmacology, 246: 112221, 2020.

3. Feng Sun, Zhendong Wang, Zhifang Yang, Yan Li, Huifei Cui, Chunhui Liu, DezongGao, Fengshan Wang, and Haining Tan*. Characterization, bioactivity and pharmacokinetic study of a novel carbohydrate-peptide polymer: glycol-split heparin-endostatin2 (GSHP-ES2). Carbohydrate Polymers, 207, 79-90, 2019.

4. Zhendong Wang, Yan Li, Liang Xing, Feng Sun, Zhifang Yang, Fengshan Wang, and Haining Tan*. Effects of the anti-angiogenic carbohydrate-peptide conjugate, chitooligosaccharide-ES2 on endothelial cells and tumor-bearing mice. Carbohydrate Polymers, 208, 302-313, 2019.

5. Liang Xing, Feng Sun, Zhendong Wang, Yan Li, Zhifang Yang, Fengshan Wang, and Haining Tan*. Characterization and bioactivity of self-assembled anti-angiogenic chondroitin sulfate-ES2-AF nanoparticle conjugate. International Journal of Nanomedicine, 14, 2573–2589, 2019.

6. Zhifang Yang, Yan Li, Feng Sun, Huiwen Hou, Liang Xing, Zhendong Wang, FengshanWang, Haining Tan*. Improved stability and enhanced anti-tumor activity of hyaluronic acid modified ES2-AF nanoparticle-like conjugate. Journal of Biomedical Nanotechnology, 15, 1781–1791, 2019.

7. Yuanxiu Liu, Abdur Rauf Khan, Xiyou Du, Yujia Zhai, Haining Tan*, and Guangxi Zhai*. Progress in the polymer-paclitaxel conjugate. Journal of Drug Delivery Science and Technology, 54, 101237, 2019.

8. Feng Sun, Yang Yu, Zhifang Yang, Zhendong Wang, Yan Li, Fengshan Wang, and Haining Tan*. Hyaluronic acid-endostatin2-alft1 (HA-ES2-AF) nanoparticle-like conjugate for the target treatment of diseases. Journal of Controlled Release, 288,1-13, 2018.

9. Feng Sun, Abdul Sami Shaikh, Juan Wang, Hui Gao, Zhifang Yang, Zhendong Wang, Yan Li, Fengshan Wang, and Haining Tan*. Higher Anti-angiogenesis Activity, Better Cellular Uptake and Longer Half-life of a Novel Glyco-modified Endostatin by Polysulfated Heparin. Current Pharmaceutical Biotechonology,  19(12): 996 - 1004, 2018.

10. Yang Yu, Feng Sun, Congcong Zhang, Zhendong Wang, Jinfeng Liu, and Haining Tan*. Study on glyco-modification of endostatin-derived synthetic peptide endostatin2 (ES2) by soluble chitooligosaccharide. Carbohydrate Polymers, 154, 204-213, 2016.

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